Regardless of the cell type (fibroblasts, vascular smooth muscle cells, endothelial cells, cancer cells, astrocytes, platelets, mesenchymal stem cells) and the senescence inducer (serial passages, oxidative stress, DNA-damaging drugs, X-ray irradiation), angptl2 expression either increased or decreased in senescent cells (Table 1). This evidence concerns the gene ANGPTL2 and cancer.