The resulting protein expression levels of EGFR and SQSTM1 in tumor tissue of all OSCC patients including buccal mucosa squamous cell carcinoma (BMSCC) and tongue squamous cell carcinoma (TSCC) patients were significantly higher than those in the CTAN tissues (all p < 0.001, Table 1). This evidence concerns the gene SQSTM1 and squamous cell carcinoma of buccal mucosa.