MiR-21 and miR-93 are involved in inflammatory and apoptotic signaling pathways and were found downregulated in PBMCs of T1DM patients, whereas miR-326, which targets significant modulators of the immune system—vitamin D receptor (VDR) and erythroblastosis virus E26 oncogenic homolog 1 (ETS-1)—was overexpressed in PBMCs of T1DM patients, further implicating the role of miRNAs in T1DM autoimmunity. Here, VDR is linked to type 1 diabetes mellitus.