In the group of subjects with type 1 diabetes (<3 months from diagnosis), a negative correlation was found between the percentage and the number of B lymphocytes with the CD19+ TLR9+ phenotype, as well as the percentage and the number of T lymphocytes with the CD8+ TLR9+ phenotype with HbA1c and the concentration of fructosamine. Here, CD8A is linked to type 1 diabetes mellitus.