Among the revealed potential markers, the overrepresentation of ribonuclease 2 and underrepresentation of haptoglobin may suggest the worst FSGS prognosis, whereas apolipoprotein A1 and matrix-remodeling protein 8 (MXRA8) showed significant changes between steroid-sensitive and steroid-resistant forms of FSGS [51]. This evidence concerns the gene RNASE2 and focal segmental glomerulosclerosis.