Furthermore, data comparing stable and ICU patients indicated lower IL-10 concentrations in the former, revealing that while other cytokines involved in innate immunity, such as IL-1β, IL-6, IL-8, and sTNFR1, show high secretion levels in all COVID-19 patients, IL-10 levels are significantly higher in critical patients. This evidence concerns the gene CXCL8 and COVID-19.