In the univariate analysis, for ghrelin age (R2 = 0.166, p = 0.001) and for the leptin/ghrelin ratio BMI (R2 = 0.093, p = 0.018), ponderal status (R2 = 0.088, p = 0.021), diabetes (R2 = 0.101, p = 0.013), insulin (R2 = 0.082, p = 0.026), and patient sex (R2 = 0.163, p = 0.001) were independent predictive factors. This evidence concerns the gene INS and diabetes mellitus.