For LY86-AS1, the ROC analysis showed an ability to distinguish MM patients from PCL patients with a sensitivity of 92% and specificity of 79%, with the area under the curve (AUC) = 0.8884 using the cut-off value of ≤0.0000812 (p < 0.0001) (Figure 3A). Here, LY86 is linked to plasma cell leukemia.