IFNA2 and chronic myelogenous leukemia, BCR-ABL1 positive: Below, we discuss IFN-α’s role in treatment of the main myeloid malignancies: the myeloproliferative neoplasms (chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), as well as in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).