IFNG and Alzheimer disease: A recent model-based meta-analysis of clinical trials allowed the development of a mathematical model that reproduced the reported clinical efficacy of nine biological drugs (dupilumab, lebrikizumab, tralokinumab, secukinumab, fezakinumab, nemolizumab, tezepelumab, GBR 830, and recombinant interferon-gamma) by describing the system-level pathogenesis of AD.