However, significantly reduced inhibitory TIGIT expression was detected only in the case of the preeclamptic CD8+ T cells, which might be a part of the Th1 predominance during EO preeclampsia at the same time, the expression of the activatory counterpart CD226 also exhibited a decreased pattern in preeclampsia, not only the CD8+ T cells, but also in all investigated cell population. This evidence concerns the gene CD226 and preeclampsia.