As a sponge of miR-874-3p, the overexpression of circ_0007142 in CRC prevents the inhibition of miR-874-3p on the target glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5), thereby promoting the apoptosis of CRC [108]. The gene discussed is GDPD5; the disease is colorectal carcinoma.