PIK3CA and breast cancer: Moreover, some genes were found to be commonly involved in both BC and CRC regulation, such as BRAF, PIK3CA, ERBB2, TP53, PTEN, FGFR1, ERBB3, neuregulin 1 (NRG1), GNAS, KDR, and PSMD4, which are regulated by miR-338-3p, miR-375, and miR-149-5p.