MAP2K1 and glioblastoma: Circ_ASAP1 promotes tumorigenesis and the temozolomide (TMZ) resistance of glioblastoma via the NRAS proto-oncogene, GTPase (NRAS)/mitogen-activated protein kinase kinase 1 (MEK1)/extracellular signal-regulated kinase 1 and 2 (ERK1-2) signaling pathway [136].