We used the cBioPortal database to query the genetic alteration profile of NSP3 (SH2D3C) in 566 lung adenocarcinoma cases (TCGA, PanCancer Atlas) and found that 2.1% of the cohorts harbored genetically altered NSP3 (SH2D3C) (Figure 2A). Here, SH2D3C is linked to lung adenocarcinoma.