SH2D3C and neoplasm: Furthermore, we queried associations of NSP3 (SH2D3C) expressions with infiltration levels of immunosuppressive cells and found that NSP3 (SH2D3C) expression was positively correlated with tumor infiltration of CAFs (r = 0.205–0.395 all p < 0.1 × 10−5), T reg cells (r = 0.231–0.143 all p < 0.05), and M2 macrophages (r = 0.535–0.414 all p < 0.1 × 10−20) in LUAD and LUSC, respectively (Figure 4D).