Hormone-insensitive prostate tumor cell lines, including PC3 and DU145, significantly express TGF-β1 and TGF-β2 among TGF-β ligands (TGF-β1, TGF-β2, and TGF-β3), but hormone-sensitive prostate tumor cell lines, including LNCaP and VCaP, do not (Cancer Cell Line Encyclopedia; CCLE). This evidence concerns the gene TGFB1 and cancer.