A different Salmonella vaccine strain, namely Salmonella enterica serovar Typhimurium vaccine (RASV), also demonstrated a CD8+ T cell-dependent antitumor activity after intratumoral injection; however, the disparity in tumor volume between CD8+ T cell-depleted mice group with and without Salmonella treatment indicates other key players in the antitumor responses [45]. Here, CD8A is linked to neoplasm.