However, it is worth noting that although there is a correlation between the clinical phenotype and antibody profile, the former cannot be regarded in absolute terms as there are cases where discrepancies exist, such as mucosal PV with Dsg1 antibodies, mucocutaneous PV without Dsg 3 antibodies, and cutaneous PV lacking Dsg3 antibodies [10]. Here, DSG3 is linked to acquired polycythemia vera.