UCP1 and hydrops fetalis: Utilizing HF diet-induced male, obese B6 mice housed at 22 °C, we reported that EPA supplementation (36 g EPA/kg of diet; 6.75% kcal fat) reduced hepatic TG accumulation [19], body weight, and adiposity [15], such an effect that was associated with increased expression of UCP1 in BAT, suggesting a possible activation of non-shivering thermogenesis [22].