WNT4 and endometriosis: Since then, more than 15 GWAS have been reported and a systematic review of GWAS in endometriosis published until the end of 2019 revealed that WNT4 rs7521902, IL1A rs6542095, FN1 rs1250248, GREB1 rs13394619, and VEZT rs10859871 variants appeared to be important as the frequency was high and in terms of pathways as well as function that each gene affected in the development of endometriosis [85].