Treatment with CIS and EQ alone or in combination showed a significant increase in total protein (p ≤ 0.05) (p ≤ 0.0001) (p ≤ 0.0001), GST (p ≤ 0.0001), TAC (p ≤ 0.0001), and catalase (p ≤ 0.01) (p ≤0.0001) (p ≤ 0.0001), respectively, in EAC cells, and showed a significant decrease in MDA (p ≤ 0.0001) as compared to the untreated group (Table 4). Here, CAT is linked to in situ carcinoma.