Pathway analysis demonstrated that the 22 differentially expressed miRNAs are related to distinct molecular pathways associated with cellular senescence, cell cycle, adherens, tight junction, atherosclerosis, TGF-β signaling, TNF-α signaling, insulin resistance, Alzheimer’s disease, and HIF-1α signaling, all of which have been found to play a role in the development of adverse consequences of OSA. The gene discussed is TNF; the disease is obstructive sleep apnea syndrome.