Finally, functional effects of two validated miRNAs (miR-15b-5p and miR-92b-3p) on oxidative stress, inflammation, and monoamine oxidase A (MAOA) were examined by a series of in vitro IHR experiments, and their implication in the treatment of OSA-related depression was investigated. The gene discussed is MAOA; the disease is obstructive sleep apnea syndrome.