The inhibition of acetylcholinesterase enzyme (AChE) activity is an indicator of neurotransmitter dysfunction in diseases such as Parkinson and Alzheimer’s disease confirmed by studies with microcapsules from Hippophaë rhamnoides determined correlations between its compounds and in-vitro anticholinergic and the antioxidant activity [18]. The gene discussed is ACHE; the disease is early-onset autosomal dominant Alzheimer disease.