Considering the essential role of autophagy in early placental development and regulation of OS and the importance of cholesterol transporters in maintaining the successful pregnancy, we hypothesized that dysregulated autophagy and oxidative stress leads to abnormal expression of selected placental membrane transporters (ABCA1, ABCG1, and ABCG2) contributing to poor pregnancy survival in EMC. This evidence concerns the gene ABCA1 and extraskeletal myxoid chondrosarcoma.