In a recent study analyzing levels of the following antioxidant and oxidative stress markers—MDA (malondialdehyde), TOS, TAC, SOD (superoxide dismutase), glutathione peroxidase and IL-6—in 30 patients newly diagnosed with type 2 diabetes and 30 systemically healthy patients, MDA, TOS and IL-6 values were significantly up marked in diabetic patients. This evidence concerns the gene SOD1 and type 2 diabetes mellitus.