PPARG and cancer: In the same type of cancer cells, CB13 (1-benzyl-5-(4-methylphenyl) pyrido [2,3-d]pyrimidine-2,4(1H,3H)-dione), a recently synthesized PPARγ ligand, reduces the radio-resistance via the production of ROS and induced apoptosis through the stimulation of caspase-3, and caspase-9 activities [199].