However interestingly, we found that the median GSH and Glu+Gln concentrations were lower, and the median Lac concentration was higher in the true-positive group than in the false-positive group, which is consistent with data that we [1,6] and others [7,8] have previously reported in IDH-mutant versus IDH-wildtype gliomas. Here, IDH1 is linked to central nervous system cancer.