THBD and blood coagulation disease: The identification of increased D-dimer (>1–2 μg/mL), increased thrombomodulin (>3.26 ng/mL), initial increase in factor V (>150 IU/dL) followed by late-stage low factor V (<150 IU/dL) or low factor VII (<200 IU/dL), and elevated IL-6 (>0.795 μg/L), LDH, and CRP have been associated with coagulopathy (such as DIC-like reactions) and cytokine storm correlated with increased mortality in patients with COVID-19 or COVID-19-associated pneumonia.