When we applied our laboratory’s standard cut-off values (CEA: 5 μg/L, CA19-9: 34 U/mL), of the 124 patients with available tumor marker levels, 34 patients (27.4%) displayed an isolated elevation of CEA and 6 patients (4.8%) had exclusively elevated levels of CA19-9. This evidence concerns the gene CEACAM5 and neoplasm.