IGHE and asthma: It is a source of IgE-mediated allergen sensitization and is related to the development and exacerbation of respiratory disease conditions such as asthma [2], rhinosinusitis [5], and allergic bronchopulmonary mycosis (ABPM) [6], as well as the so-called hypersensitivity pneumonitis, also known as extrinsic allergic alveolitis [7].