Interestingly, the analyses of inflammatory mediator patterns (SP-A, IL-1β, IFN-γ, IL-18, and IL-17A) represented either in Figure 2, Figure 3, Figure 4, Figure 5, Figure 6, Figure 7 and Figure 8 or in Figure 9 (heatmap), as well as in Table 2 and Table 3, showed that H. capsulatum and P. jirovecii co-infection resembled H. capsulatum infection, although to a lesser extent, suggesting an immunomodulatory ability of P. jirovecii against H. capsulatum host response, irrespective of the HIV status. Here, IL1B is linked to coinfection.