The clinical and histopathological presentation, genetic findings and demonstrated absence of laminin α2 protein expression in skeletal muscle together with the existing knowledge of LAMA2-related CMD in dogs [10] and other species [22,38] establish LAMA2:c.3285G>A as causative variant for the observed CMD phenotype in the investigated dog. The gene discussed is LAMA2; the disease is congenital muscular dystrophy.