The resulting AUC and cutoff values were able to differentiate NAFLD/NASH cases from controls, with AUC = 0.841 for TNF mRNA, AUC = 0.871 for MAPK3 mRNA, AUC = 0.839 for EP300 mRNA, AUC = 0.797 for EDN1 mRNA, AUC = 0.916 for miR-6888-5p miRNA and AUC = 0.844 for lncRNA RABGAP1L-DT-206. The gene discussed is EP300; the disease is metabolic dysfunction-associated steatotic liver disease.