Anti-tumor immune cells including CD4+ Th1 cells (p = 0.009), NK cells (p = 0.033), M1 macrophage cells (p = 0.007), and plasmacytoid dendritic cells (PDC) (p = 0.010) had higher proportions in the CSMD1-mut group (Figure 5C,F,G,I). Here, CD4 is linked to neoplasm.