In the transcriptome analysis, it can be observed from the differential gene enrichment results of samples treated with ω-3 fatty acids and unprocessed samples that these differential genes are significantly enriched in the genes associated with Alzheimer’s disease and longevity in the GAD_DISEASE database, enriched in mitochondria in GO and enriched in the p53 signaling pathway and FoxO signaling pathway in KEGG. The gene discussed is TP53; the disease is early-onset autosomal dominant Alzheimer disease.