We hypothesized that the risk alleles (T allele of rs11864909, G allele of rs13333226, G allele of rs4293393, and C allele of rs6497476) can contribute to the variety of levels of eGFR and serum uromodulin and may have an impact on the prognosis and complications of CKD. The gene discussed is UMOD; the disease is chronic kidney disease.