Nine genes: GLI3 (Gli-Kruppel Family Member 3; OMIM# 16540), ANLN (Actin-Binding Protein Anillin; OMIM# 616027), POU6F2 (Pou Domain, Class 6, Transcription2; OMIM# 609062), GCK (Glucokinase; OMIM#138079), CCM2 (Scaffold Protein; OMIM# 607929), IKZF1 (Ikaros Family Zinc Finger 1; OMIM# 603023), CDK13 (Cyclin-Dependent Kinase 13; OMIM# 603309), CAMK2B (Calcium/Calmodulin-Dependent Protein Kinase Ii-β; OMIM# 607707), and RALA (Ras-Like Protooncogene A; OMIM# 179550) are known to be responsible for autosomal dominant mendelian disorders, of which GLI3 is the gene causing GCPS. This evidence concerns the gene GCK and Greig cephalopolysyndactyly syndrome.