Exposure to maternal overnutrition or maternal obesity before or during gestation or lactation, leads to an incremental increase in the mRNA level of several adipogenic genes in peripheral fat in fetal sheep such as PPARG, fatty acid synthase, lipoprotein lipase, adiponectin, and leptin which participate in energy and lipid metabolism [63,64,67]. The gene discussed is ADIPOQ; the disease is overnutrition.