Furthermore, platelet-derived growth factor receptor (PDGFR)-β, proinflammatory and profibrogenic regulator, which can act as a potential target in diagnosing and treating early stages of NAFLD fibrosis [62], was hypomethylated and upregulated transcriptionally in the offspring of obese mothers [62]. This evidence concerns the gene PDGFRB and metabolic dysfunction-associated steatotic liver disease.