TP63 and neoplasm: The NCBI conserved domain search tool provided three domains of TP63 protein as follows; (1) P53 DNA binding domain (177–358 amino acid residues) usually binds to the DNA, (2) P53_tetramer domain (392–428 amino acid residues), which is described as P53 tetramerization motif according to the Pfam protein family, and (3) SAM_tumor_63 (543–607 amino acid residues), which is defined as SAM domain of tumor-p63 proteins, where SAM stands for sterile alpha motif (Figure S4).