Augmented galectin-7 during the period of placental formation in mice caused hypertension and albuminuria, and the authors hypothesize that in women, galectin-7 acts via the placenta to induce the systemic features of pre-eclampsia via impaired placental formation, placental inflammation and the placental release of anti-angiogenic factors [83]. Here, LGALS7 is linked to hypertensive disorder.