Fowler et al. [64] evaluated kinase inhibitors in transgenic mouse models of Alzheimer’s and Parkinson’s diseases and showed that combinations of nilotinib (2) (multi-kinase Abl/DDR inhibitor), LCB-03-0110 (37) (DDR/Src inhibitor) and bosutinib (7) (Abl/Src inhibitor) were superior to the more selective Abl inhibitors radotinib (6) and bafetinib (4) (Figure 9). The gene discussed is SRC; the disease is Parkinson disease.