They showed that the DDR1 inhibitor 10 (DDR1-IN-1; DDR1 enzyme IC50 105 nM) inhibited melanoma cell proliferation in both in vitro and ex vivo assays of hereditary Alport syndrome, tubular obstructive nephropathy and nephrotoxic serum glomerulonephritis, and was effective in animal melanoma xenograft models. Here, DDR1 is linked to melanoma.