Other studies have also observed higher IL-8 in patients with chronic hepatitis B or C [2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23], corroborating the role of this cytokine in the immunopathogenesis of these viral infections and the worsening of the hepatic lesion [12,13]. The gene discussed is CXCL8; the disease is viral infectious disease.