SLC25A1. Mutations in the mitochondrial citrate carrier (CIC) have recently been associated with congenital myasthenic syndromes (CMS), a heterogeneous group of neuromuscular disorders, all characterized by an impaired neuromuscular transmission, mainly due to alterations in the neuromuscular junction [233,234,235]. This evidence concerns the gene SLC25A1 and Congenital myasthenic syndromes.