MKI67 and neoplasm: Adjusting the regression model to tumor size (pT1, pT2, pT3), Nottingham histological grade (1, 2, 3) and lymph node status (pN0, pN1, pN2, pN3), all DIA Ki67 algorithms, including the reference Ki67 scoring, remained independent prognostic markers of RFS (p ≤ 0.018 for all comparisons) besides lymph node status (p ≤ 0.05).