KCNQ1OT1 and cancer: In contrast, Li et al., reported that overexpression of KCNQ1OT1 promoted apoptosis in neuroblastoma cells by sponging miR296-5p and upregulating BCL2 Associated X (Bax), a key regulator of cell death [12], suggesting a cancer cell type-dependent role of KCNQ1OT1.