CDKN2B-AS1 and coronary artery disorder: Among these markers, ANRIL in particular showed to be the leading candidate contributing to the relationship between 9p21 regions and CAD, since a transcriptomic analysis of circulating leukocytes demonstrated that the expression of short variants of ANRIL increased by 2.2 fold whereas the expression of the long ANRIL variants decreased by 1.2 fold in healthy subjects homozygous for the risk allele.