MGMT and glioblastoma: The present study aimed to quantify in vitro the tumoricidal, temozolomide-, and radio-sensitizing function of disulfiram/Cu2+ on cell cycle distribution and clonogenic survival of isocitrate dehydrogenase (IDH) wildtype, O6-methylguanine-DNA-methyltransferase (MGMT) promoter-unmethylated, temozolomide-resistant glioblastoma stem cells grown in primary culture.