Moreover, different from intrathecal IgG restricted bands, which mainly target non-self-antigens (measles, rubella, mumps, and many others [46]), a subset of intrathecal IgM target myelin lipids (in most cases phosphatidylcholine, followed by phosphatidylinositol, gangliosides, and sulphatides [29,31,47]). Here, CD40LG is linked to measles.