Moreover, another multicenter study presented the interest of CAZ-AVI in salvage therapy in the largest sample to date of patients with infections caused by carbapenem-resistant Gram-negative bacteria, 97% of which included KPC Klebsiella pneumoniae (KPC-Kp), while 75.4% were bacteremia and 4.3% were UTI alone. This evidence concerns the gene NPPA and bacterial infectious disease with sepsis.