At 72 hpi, the up-regulated DEGs could be functionally classified into “toll-like receptor signaling pathway” and “RIG-I-like receptor signaling pathway”, pathogen infection-related pathways, “apoptosis”, and several metabolism-related pathways (Figure 3), while the down-regulated DEGs mainly participated in important metabolism-related pathways such as “insulin signaling pathway” and “adipocytokine signaling pathway” (Figure 3). Here, INS is linked to infection.