Presently, tumor immune escape is a hallmark of tumor growth [1] and involves tumor expression of inhibitory immune checkpoints or “don’t eat me” signals such as programmed cell death ligand 1 (PD-L1), β2-microglobulin (β2 m), CD24, and CD47 to evade immune responses [2,3,4,5]. Here, CD274 is linked to neoplasm.