The EGFR locus (7p11.2) had gains in 14 biopsies; the PTEN locus (10q23.31) was affected in 14 samples (13 losses and 1 gain); 3 samples had a gain in the PDGFRA locus (4q12), while 2 tumors lost in the NF1 locus (17q11.2); one tumor had a gain in the 5q13.1 locus (PIK3R1), but none had alterations in the 3q26.32 locus (PIK3CA). The gene discussed is PIK3R1; the disease is neoplasm.